NPR's Your Picks: The Top 100 Science-Fiction, Fantasy books.
And a little bit of discussion about what the results were and how they were tabulated.
Now, some questions on how to complete the challenge.
1. Should I read from the end to the beginning, saving the "best" for last?
2. If a book is part of a series, but is not listed as such (i.e. Ender's Game is listed alone, but The Wheel of Time is listed as a series) do I have to read all of them?
Edit: Here's a nice flowchart for you, too.